PT-141 demonstrates unique efficacy in addressing erectile dysfunction through its action on the central nervous system, rather than relying on peripheral blood flow enhancement
In preclinical studies, PT-141 was shown to activate melanocortin-4 receptors (MC4R) in the hypothalamus, stimulating physiological responses associated with arousal. These effects have been noted even in the absence of stimuli that typically engage peripheral vasodilation.
Research exploring the role of PT-141 in female models has demonstrated a notable increase in sexual motivation and behavior.
It targets the brain’s pathways involved in sexual desire and arousal, addressing the root cause of a low libido.
It works directly on the brain’s pathways to restore sexual desire and arousal, unlike traditional treatments that only focus on blood flow.
Oxytocin is a naturally occurring peptide made up of nine amino acids. It is produced in the hypothalamus and released through the central nervous system. Commonly called the “bonding hormone” or “connection molecule,” oxytocin plays a key role in social interaction, emotional communication, and the development of trust and relationships.
It binds to oxytocin receptors found in the brain, reproductive tissues, and cardiovascular system. This triggers pathways that affect mood, bonding, sexual function, and muscle contraction.
Stimulates smooth muscle contractions (important for childbirth, milk let-down, and sexual response).
Appetite Regulation – Oxytocin enhances the effect of leptin (the hormone that signals fullness) and reduces activity of ghrelin (the hunger hormone). It reduces food intake by increasing the feeling of satiety after meals.
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